November 27, 2013 – 9:35 am
Baboons vaccinated against whooping cough could still carry the illness in their throats and spread it, research published in a science journal on Monday has found. The surprising new finding has not been replicated in people, but scientists say it may provide an important clue to a puzzling spike in the incidence of whooping cough across the country, which reached a 50-year high last year.
November 27, 2013 – 9:28 am
Dogs with the bleeding disorder hemophilia A have been successfully treated by gene therapy, according to US scientists. Two of three dogs given the experimental treatment remain free of severe symptoms more than two years on, they write in Nature Communications. Hemophilia A is a bleeding disorder which affects one in 10,000 men. Gene therapy may be suitable for human treatment for bleeding disorders in 10 years, says the Hemophilia Society.
November 26, 2013 – 11:30 am
If you’ve ever experienced the three-part Hepatitis B vaccine series, or – heaven forbid – the multi-jab rabies course, you know the joy of being turned into a human pincushion. Even if you don’t mind needles, each booster shot means another trip to the doctor’s office. But now scientists have come up with a remote-controlled vaccine delivery system that eliminates the need for follow-up injections. The new system uses a single shot to deliver a small and squishy, vaccine-containing hydrogel sphere to a spot beneath the skin. Then, instead of booster shots, swallowing a pill releases additional doses of vaccine. So in theory, instead of going back to the clinic for more syringe action, you could simply set a reminder on your phone and pop a pill.
November 25, 2013 – 9:50 am
Wits researchers Maria Papathanasopoulos and Dr Penny Moore will present a research lecture on their internationally recognised work at Wits University on Tuesday. Though condoms and male circumcision work to prevent HIV, about 1000 South Africans are still infected every day, said Papathanasopoulos.
November 22, 2013 – 1:25 pm
A newly formed gene therapy startup is taking gene delivery technology from ReGenX and a $5 million investment from Fidelity Biosciences to develop new treatments for rare diseases, starting with hemophilia. ReGenX and Fidelity Biosciences announced the launch of Dimension Therapeutics at the end of last month and disclosed the $5 million Series A fundraise in an SEC filing this week.
November 22, 2013 – 1:23 pm
In this clinical trial, a new immunotherapy vaccine is being administered to dogs that have already undergone standard treatment for osteosarcoma: limb amputation and chemotherapy. The aim of the vaccine is to prevent metastatic disease and prolong overall survival. Typically, 60 percent of such dogs die within one year of diagnosis. But of the first five dogs vaccinated, four are still alive. Sasha has lived 607 days and the other dogs in the trial have survived between 500 and 590 days. Three are tumor free.
Inovio Pharmaceutical’s DNA Vaccine for the Deadly MERS Virus Induces Robust Immune Response in Preclinical Trial
November 22, 2013 – 1:09 pm
Inovio Pharmaceuticals, Inc. announced that preclinical testing of a DNA synthetic vaccine for the virulent Middle East Respiratory Syndrome coronavirus (MERS) induced robust and durable immune responses, demonstrating the potential for a SynCon DNA vaccine to prevent and treat this deadly virus. Since 2012, when the virus was first identified, 153 cases from nine Middle Eastern countries have been reported and, alarmingly, 42% of these cases have been fatal. MERS is similar to the SARS virus which infected 8,000 people several years ago. MERS differs from SARS in that it appears to be less contagious, but MERS is almost five times as fatal as SARS, which killed 10% of those infected. There is no vaccine or effective treatment for MERS.
DNAVaccine.com Presents: Designing an Epitope-Driven Vaccine for a “Stealth Virus” an H7N9 Case Study
November 21, 2013 – 2:53 pm
We are happy to once again bring you the opportunity to join us for a free online webinar. The upcoming webinar: ‘Designing an Epitope-Driven Vaccine for a "Stealth Virus" an H7N9 Case Study’ will be presented by Annie De Groot, MD of EpiVax, Inc. on December 6th. For additional information and to register please read on!
November 20, 2013 – 8:51 am
A stem cell therapy previously shown to reduce inflammation in the critical time window after traumatic brain injury also promotes lasting cognitive improvement, according to preclinical research led by Charles Cox, MD, at The University of Texas Health Science Center at Houston (UTHealth) Medical School.
November 20, 2013 – 8:40 am
For decades, researchers have been finding DNA and its sister, RNA, circulating in the body, outside the safe interior of cells where these molecules do their essential work of storing and translating the code of life. The reasons for these molecular voyages have remained mysterious, but in recent years evidence has accrued that this extracellular RNA may have a different job, at least in some organisms.